Synthetic gene circuits moving into the clinic
نویسندگان
چکیده
منابع مشابه
Synthetic biology moving into the clinic.
Synthetic biology is an emerging field focused on engineering biomolecular systems and cellular capabilities for a variety of applications. Substantial progress began a little over a decade ago with the creation of synthetic gene networks inspired by electrical engineering. Since then, the field has designed and built increasingly complex circuits and constructs and begun to use these systems i...
متن کاملSynthetic Gene Circuits
Barbara Jusiak1,2, Ramiz Daniel1,3, Fahim Farzadfard2–5, Lior Nissim1,3, Oliver Purcell2,3, Jacob Rubens1,3,5, and Timothy K. Lu1–6 1Massachusetts Institute of Technology, Research Laboratory of Electronics, Cambridge, MA 02139, USA 2Massachusetts Institute of Technology, Department of Biological Engineering, Cambridge, MA 02139, USA 3Massachusetts Institute of Technology, Synthetic Biology Cen...
متن کاملSynthetic biology: integrated gene circuits.
A major goal of synthetic biology is to develop a deeper understanding of biological design principles from the bottom up, by building circuits and studying their behavior in cells. Investigators initially sought to design circuits "from scratch" that functioned as independently as possible from the underlying cellular system. More recently, researchers have begun to develop a new generation of...
متن کاملInfant lung function testing--moving into the clinic now?
Accessible online at: www.karger.com/journals/res The papers by Wildhaber et al. [1] and Lagerstrand et al. [2] in this issue of Respiration indicate that assessment of airway function may soon become a routine procedure for the evaluation of infants with chest disease and the assessment of response to therapy. Lung function tests for adults were developed to a large extent during the 1950s and...
متن کاملMoving a Carbohydrate Mimetic Peptide into the clinic.
Tumor-Associated Carbohydrate Antigens (TACAs) are broad-spectrum targets for immunotherapy. Immunization with Carbohydrate Mimetic Peptides (CMPs) is a strategy to induce broad-spectrum TACA-reactive antibodies hypothesized to interfere with cellular pathways involved in tumor cell survival. A Phase I study was conducted with a first-in-man CMP referred to as P10s, conjugated to the Pan T cell...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Quantitative Biology
سال: 2021
ISSN: 2095-4689
DOI: 10.15302/j-qb-021-0234